Group Leader/s

 

intro

Main research focus in our lab is the characterization of cell adhesion, migration and invasion in response to chemokines, both under physiological and pathological conditions.

 

Bartolomé RA, Torres S, Isern de Val S, Escudero-Paniagua B, Calviño E, Teixidó J, Casal JI.  [2017]. VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers. Oncotarget. 8: 215-227.

M Martínez-Moreno, M Leiva, N Aguilera-Montilla, S Sevilla-Movilla, S I de Val, N Arellano-Sánchez, N C Gutiérrez, R Maldonado, J Martínez-López, I Buño, J A García-Marco, P Sánchez-Mateos, A Hidalgo, A García-Pardo and J Teixidó  [2016]. In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins. 2016. Leukemia, 30, 861-872

Sosa-Costa A, Isern de Val S, Sevilla-Movilla S, Borgman KJ, Manzo C, Teixidó J, Garcia-Parajo MF.  [2016]. Lateral Mobility and Nanoscale Spatial Arrangement of Chemokine-activated α4β1 Integrins on T Cells. J Biol Chem. 291: 21053-21062

Gutiérrez-González A, Martínez-Moreno M, Samaniego R, Arellano-Sánchez N, Salinas-Muñoz L, Relloso M, Valeri A, Martínez-López J, Corbí ÁL, Hidalgo A, García-Pardo Á, Teixidó J, Sánchez-Mateos P.  [2016]. Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma. Blood. 128: 2241-2252

Dios-Esponera A, Isern de Val S, Sevilla-Movilla S, García-Verdugo R, García-Bernal D, Arellano-Sánchez N, Cabañas C, Teixidó J.  [2015]. Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T lymphocyte adhesion mediated by integrin α4β1. Mol Biol Cell. 2015 Jul 22. pii: mbc.E14-07-1246. PMID: 26202465

Bartolomé R.A., Díaz-Martínez M., Coló G.P., Arellano-Sánchez N., Torres-Ayuso P., Kleinovink J.W., Mérida I. y Teixidó J.  [2014]. A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion. Cell Signal. 2014 Nov;26(11):2551-61. doi: 10.1016/j.cellsig.2014.07.008. Epub 2014 Jul 13. PMID: 25025568

Coló GP, Lafuente EM, Teixidó J  [2012]. The MRL proteins: Adapting cell adhesion, migration and growth. Eur J Cell Biol. 2012 Nov;91(11-12):861-8. 2012 May 1

García-Bernal D, Redondo-Muñoz J, Dios-Esponera A, Chèvre R, Bailón E, Garayoa M, Arellano-Sánchez N, Gutierrez NC, Hidalgo A, García-Pardo A, Teixidó J  [2012]. Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function. J Pathol. 2013 Jan;229(1):36-48. doi: 10.1002/path.4066.

 

Funding

- Imaging, genomics and proteomics analyses of B cell hematological tumor progression

S2010/BMD-2314. Biomedicina. Comunidad de Madrid. 2012-2016

Principal Investigator, Joaquin Teixido Calvo

- Spanish Network of Cooperative Research in Cancer

Ministry of Health RD12/0036/0061 (2012-2017)

Principal Investigator, Joaquin Teixido Calvo

- Characterization of molecular pathways controlling cell motility in leukocyte trafficking and tumor cell invasion

SAF2014-53059-R: 2015-2017

Principal Investigator, Joaquin Teixidó

 

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