Group Leader/s
Head of lab
intro
Main research focus in our lab is the characterization of cell adhesion, migration and invasion in response to chemokines, both under physiological and pathological conditions.
Members
| Joaquín Teixidó Calvo |
| Nohemí Arellano Sánchez |
| Silvia Sevilla Movilla |
| Lucia Benito Jardón |
Selected Publications
Díaz-Martínez M, Benito-Jardón L, Alonso L, Koetz-Ploch L, Hernando E, Teixido J. [2018]. miR-204-5p and miR-211-5p contribute to BRAF inhibitor resistance in melanoma. Cancer Research, 78: 1017-1030.
Teixidó J, Martínez-Moreno M, Díaz-Martínez M, Sevilla-Movilla S. [2017]. The good and bad faces of the CXCR4 chemokine receptor. Int J Biochem Cell Biol. 95:121-131
Bartolomé RA, Torres S, Isern de Val S, Escudero-Paniagua B, Calviño E, Teixidó J, Casal JI. [2017]. VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers. Oncotarget. 8: 215-227.
Gutiérrez-González A, Martínez-Moreno M, Samaniego R, Arellano-Sánchez N, Salinas-Muñoz L, Relloso M, Valeri A, Martínez-López J, Corbí ÁL, Hidalgo A, García-Pardo Á, Teixidó J, Sánchez-Mateos P. [2016]. Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma. Blood. 128: 2241-2252
Sosa-Costa A, Isern de Val S, Sevilla-Movilla S, Borgman KJ, Manzo C, Teixidó J, Garcia-Parajo MF. [2016]. Lateral Mobility and Nanoscale Spatial Arrangement of Chemokine-activated α4β1 Integrins on T Cells. J Biol Chem. 291: 21053-21062
M Martínez-Moreno, M Leiva, N Aguilera-Montilla, S Sevilla-Movilla, S I de Val, N Arellano-Sánchez, N C Gutiérrez, R Maldonado, J Martínez-López, I Buño, J A García-Marco, P Sánchez-Mateos, A Hidalgo, A García-Pardo and J Teixidó [2016]. In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins. 2016. Leukemia, 30, 861-872
Dios-Esponera A, Isern de Val S, Sevilla-Movilla S, García-Verdugo R, García-Bernal D, Arellano-Sánchez N, Cabañas C, Teixidó J. [2015]. Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T lymphocyte adhesion mediated by integrin α4β1. Mol Biol Cell. 2015 Jul 22. pii: mbc.E14-07-1246. PMID: 26202465
Bartolomé R.A., Díaz-Martínez M., Coló G.P., Arellano-Sánchez N., Torres-Ayuso P., Kleinovink J.W., Mérida I. y Teixidó J. [2014]. A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion. Cell Signal. 2014 Nov;26(11):2551-61. doi: 10.1016/j.cellsig.2014.07.008. Epub 2014 Jul 13. PMID: 25025568
Funding
- Imaging, genomics and proteomics analyses of B cell hematological tumor progression
S2010/BMD-2314. Biomedicina. Comunidad de Madrid. 2012-2016
Principal Investigator, Joaquin Teixido Calvo
- Spanish Network of Cooperative Research in Cancer
Ministry of Health RD12/0036/0061 (2012-2017)
Principal Investigator, Joaquin Teixido Calvo
- Characterization of molecular pathways controlling cell motility in leukocyte trafficking and tumor cell invasion
SAF2014-53059-R: 2015-2017
Principal Investigator, Joaquin Teixidó