RMN Biomolecular | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

Volver

Head of lab

Francisco Jose Blanco Gutierrez

Ver Proyectos actuales Ver Proyectos anteriores

Molecular recognition in DNA replication and repair

Structure-function of ING tumor suppressors

Targeting non-GPCR regulation of G proteins to stop cancer

Personal Científico
Francisco Jose Blanco Gutierrez

Postdoctorals
Belen Chaves Arquero

Predoctorales
Antonio Ruiz Albor
Maria de la O Ferreras Gutierrez

Group

O Hangiu, M Compte, A Dinesen, R Navarro, A Tapia-Galisteo, OA Mandrup, A Erce-Llamazares, R Lázaro-Gorines, D Nehme-Álvarez, C Domínguez-Alonso, SL Harwood, C Alfonso, B Blanco, L Rubio-Pérez, A Jiménez-Reinoso, L Díez-Alonso, FJ Blanco, L Sanz, KA Howard, L Álvarez-Vallina [2022]. A tumor target-dependent 4-1BB agonist antibody fused to albumin engineered for enhanced FcRn binding induces anti-tumor immunity without toxicity. iScience 25, 104958.

B Chaves-Arquero, C Persson, N Merino, J Tomás-Cortazar, AL Rojas, J Anguita, FJ Blanco [2022]. Structural Analysis of the Black-Legged Tick Saliva Protein Salp15. International Journal of Molecular Sciences. 23, 3134.

Tapia-Galisteo A, Sánchez Rodríguez Í, Aguilar-Sopeña O, Harwood SL, Narbona J, Ferreras Gutierrez M, Navarro R, Martín-García L, Corbacho C, Compte M, Lacadena J, Blanco FJ, Chames P, Roda-Navarro P, Álvarez-Vallina L, Sanz L [2022]. Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer. OncoImmunology. 11:2034355.

Compte M, Harwood SL, Erce-Llamazares A, Tapia-Galisteo A, Romero E, Ferrer I, Garrido-Martin EM, Enguita AB, Ochoa MC, Blanco B, Oteo M, Merino N, Nehme-Álvarez D, Hangiu O, Domínguez-Alonso C, Zonca M, Ramírez-Fernández A, Blanco FJ, Morcillo MA, Muñoz IG, Melero I, Rodriguez-Peralto JL, Paz-Ares L, Sanz L, Alvarez-Vallina L [2021]. An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity. Clin Cancer Res 27, 3167-3177.

Romero JA, Nawrocka EK, Shchukina A, Blanco FJ, Diercks T, Kazimierczuk K [2020]. Non‐Stationary Complementary Non‐Uniform Sampling (NOSCO NUS) for Fast Acquisition of Serial 2D NMR Titration Data. Angew Chem Int Ed Engl 132, 23702.

Bruzzone C, Loizaga-Iriarte A, Sánchez-Mosquera P, Gil-Redondo R, Astobiza I, Diercks T, Cortazar AR, Ugalde-Olano A, Schäfer H, Blanco FJ, Unda M, Cannet C, Spraul M, Mato JM, Embade N, Carracedo A, Millet O. [2020]. 1H NMR-Based Urine Metabolomics Reveals Signs of Enhanced Carbon and Nitrogen Recycling in Prostate Cancer. J Proteome Res 19, 2419-2428.

González-Magaña A, Blanco FJ. [2020]. Human PCNA Structure, Function and Interactions. Biomolecules 10, 570

Lancey C, Tehseen M, Raducanu VS, Rashid F, Merino N, Ragan TJ, Savva CG, Zaher MS, Shirbini A, Blanco FJ, Hamdan SM, De Biasio A. [2020]. Structure of the processive human Pol δ holoenzyme. Nature Commun 11, 1109

Palacios A, Blanco FJ [2020]. Macromolecular crowding increases the affinity of the PHD of ING4 for the histone H3K4me3 mark. Biomolecules 10, 234

González-Magaña A, de Opakua AI, Merino N, Monteiro H, Diercks T, Murciano-Calles J, Luque I, Bernadó P, Cordeiro TN, Biasio A, Blanco FJ. [2019]. Double Monoubiquitination Modifies the Molecular Recognition Properties of p15(PAF) Promoting Binding to the Reader Module of Dnmt1. ACS Chem Biol 14, 2315-2326.

Todas las publicaciones

Currently no information is available