Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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Spínola-Amilibia M, Rivera J, Ortiz-Lombardía M, Romero A, Neira JL, Bravo J. [2011]. The structure of BRMS1 nuclear export signal and SNX6 interacting region reveals a hexamer formed by antiparallel coiled coils. J Mol Biol 411:1114-1127

Gabius HJ, André S, Jiménez-Barbero J, Romero A, Solís D. [2011]. From lectin structure to functional glycomics: principles of the sugar code. Trends Biochem Sci 36:298-313

Miki Y, Calviño FR, Pogni R, Giansanti S, Ruiz-Dueñas FJ, Martínez MJ, Basosi R, Romero A, Martínez AT. [2011]. Crystallographic, kinetic, and spectroscopic study of the first ligninolytic peroxidase presenting a catalytic tyrosine. J Biol Chem 286:15525-15534

Bou G, Santillana E, Sheri A, Beceiro A, Sampson JM, Kalp M, Bethel CR, Distler AM, Drawz SM, Pagadala SR, van den Akker F, Bonomo RA, Romero A, Buynak JD. [2010]. Design, synthesis, and crystal structures of 6-alkylidene-2´-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J Am Chem Soc 132:13320-13331

Solís D, Maté MJ, Lohr M, Ribeiro JP, López-Merino L, André S, Buzamet E, Cañada FJ, Kaltner H, Lensch M, Ruiz FM, Haroske G, Wollina U, Kloor M, Kopitz J, Sáiz JL, Menéndez M, Jiménez-Barbero J, Romero A, Gabius HJ [2010]. N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution. Int J Biochem Cell Biol 42(6):1019-29

Fernández IS, Cuevas P, Angulo J, López-Navajas P, Canales-Mayordomo A, González-Corrochano R, Lozano RM, Valverde S, Jiménez-Barbero J, Romero A, Giménez-Gallego G. [2010]. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J Biol Chem. 285(15):11714-29

Fernandez IS, Ständker L, Mägert H-J, Forssmann W-G, Gimenez-Gallego G, Romero A [2008]. Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6). J Mol Biol 377, 1488-1497

Perez-Llanera FJ, Cartelle M, Mallo S, Beceiro A, Perez A, Villanueva R, Romero A, Bonnet R, Bou G [2008]. Structure-function studies of arginine at position 276 in CTX-M beta-lactamases. J Antimicrob Chem 61, 792-797

Fernández IS, Ständker L, Forssmann W-G, Giménez-Gallego G, Romero A [2007]. Crystallization and preliminary crystallographic studies of human kallikrein 7, a serine protease of the multigene kallikrein family. Acta Cryst F63:669-672

Santillana E, Beceiro A, Bou G, Romero A [2007]. Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis. PNAS 104, 5354-5359

Canales, A.; J. Angulo, R. Lozano, R. Ojeda, R. Fayos, M. Martín-Lomas, G. Jiménez-Gallego, P. M. Nieto, J. Jiménez-Barbero [2005]. Conformational Flexibility of a Synthetic Glycosylaminoglycan Bound to a Fibroblast Growth Factor. FGF-1 Recognizes both the 1C4 and 2SO Conformations of a Bioactive Heparin-like Hexasaccharide. J. Am. Chem. Soc, 2005, 127, 5778-5779

Fernandez-Tornero C, Garcia E, de Pascual-Teresa B, Lopez R, Gimenez-Gallego G, Romero A [2005]. Ofloxacin-like antibiotics inhibit pneumococcal cell wall-degrading virulence factors. J Biol Chem. 2005; 280: 19948-57

Fernández-Tornero C, Lozano RM, Rivas G, Jiménez MA, Standker L, Díaz-González D, Forssman WG, Cuevas P, Romero A, Giménez-Gallego G [2005]. Synthesis of the blood circulating C-terminal fragment of insulin-like growth factor (IGF)-binding protein-4 in its native conformation. Crystallization, heparin and IGF binding, and osteogenic activity. J Biol Chem 280:18899-19907

López-Lucendo, M.F., Solís, D., André, S., Hirabayashi, J., Kasai, K., Kaltner, H., Gabius, H.-J. and Romero, A [2004]. Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding. J Mol Biol 343, 957-970

Vargas, R., Mateu, L. and Romero, A [2004]. The effect of increasing concentrations of precipitating salts used to crystallize proteins on the structure of the lipidic Q224 cubic phase. Chem Phys Lipids. (2004) 127, 103-111

Reyes-Grajeda, J.P., Moreno, A. and Romero, A [2004]. Crystal structure of ovocleidin-17, a major protein of the calcified Gallus gallus eggshell: implications in the calcite mineral growth pattern. J. Biol. Chem. (2004) 279, 40876-40881

López-Lucendo, M. F., Guillermo Giménez-Gallego, Douglas N. W. Cooper, Hans-Joachim Gabius and Antonio Romero [2004]. Gene design, expression, crystallization and preliminary diffraction analysis of two isolectins from the fungus Coprinus cinereus: a model for studying functional diversification of galectins in the same organism and ... Acta Cryst. (2004). D60, 721-724

Giraldo, R., Fernández-Tornero, C., Evans, P.R., Díaz-Orejas, R. and Romero, A [2003]. A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain. Nature Struc. Biol. (2003) 10, 565-571

Fernández-Tornero, C., Rosa M. Lozano, Mariano Redondo-Horcajo, Ana M. Gómez, José C. López, Ernesto Quesada, Clara Uriel, Serafín Valverde, Pedro Cuevas, Antonio Romero and Guillermo Giménez-Gallego [2003]. Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate. J. Biol. Chem. 278 (2003) 21774-21781

Lostao, A., Daoudi, F., Irun, M.P., Ramón, A., Fernández-Cabrera, C., Romero, A. and Sancho, J. [2003]. How FMN binds to anabaena apoflavodoxin: a hydrophobic encounter at an open binding site. J. Biol. Chem. (2003) 278, 24053-24061