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Kalnins, T.; Vitkovska, V.; Kazak, M.; Zelencova-Gopejenko, D.; Ozola, M.; Narvaiss, N.; Makrecka-Kuka, M.; Domračeva, I.; Kinens, A.; Gukalova, B.; Konrad, N.; Aav, R.; Bonato, F.; Lucena-Agell, D.; Díaz, J.F.; Liepinsh, E.; Suna E.
[2024]. Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide J. Med. Chem., 67, 9227−9259.
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[2024]. PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin. J. Med. Chem. (2024) 67, 2619−2630
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[2023]. Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells. Pharmaceuticals (2023) 16, 1579.
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[2023]. Modulation of taxane binding to tubulin curved and straight conformations by systematic 3’N modification provides for improved microtubule binding. Eur. J. Med. Chem. (2023) 259 e115668 persistent cytotoxicity and in vivo potency
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[2023]. Probing a Distinct Druggable Tubulin Binding Site with Gatorbulins 1-7, Their Metabolic and Physicochemical Properties, and Pharmacological Consequences. Bioorg. Med. Chem. (2023) 95, 117506.
Alonso, A.; Alcolea, P.J.; Larraga, J.; Peris, M.P.; Esteban, A.; Cortés, A.; Ruiz-García, S.; Castillo, J.A.; Larraga, V.
[2023]. A non-replicative antibiotic resistance-free DNA vaccine delivered by the intranasal route protects against canine leishmaniasis. Front Immunol.,18:14:1213193.
Alcolea, P.J.*, Alonso, A*.; García-Tabares, F.; Larraga, J.; Martins, L.T.C.; Loayza, F.J.; Ruiz-García, S.; Larraga, V.
[2023]. An insight into differential protein abundance throughout Leishmania donovani promastigote growth and differentiation. Int Microbiol., 26(1):25-42.
Brütsch, T.M.; Etienne Cotter, E.; Lucena-Agell, D.; Redondo-Horcajo, M.; Davies, C.; Pfeiffer, B.; Pagani, S.; Berardozzi, S.; Díaz, J.F.; Miller, J.H.; Altmann, K.-H.
[2023]. Synthesis and Structure-Activity Relationship Studies of C(13)-Desmethylene-(–)-Zampanolide Analogs Chemistry: An European Journal. (2023) e202300703
Prota, A.E.; Lucena-Agell, D.; Ma, Y.; Estévez-Gallego, J.; Shuo, L.; Bargsten, K.; Josa-Prado, F.; Altmann, K.-H.; Gaillard, N.; Kamimura, S.; Mühlethaler, T.; Gago, F., Oliva, M.A.; Steinmetz, M.A.; Fang, W.-S.; Díaz, J. F.
[2023]. Structural insight into the stabilization of microtubules by taxanes eLife (2023) 12 e84791
Estévez-Gallego, J.; Álvarez-Bernad, B.; Pera, B.; Wullschleger, C.; Raes, O.; Menche, D.; Martínez, J.C.; Lucena-Agell, D.; Prota, A.E.; Bonato, F.; Bargsten, K.; Cornelus, J.; Giménez-Abián, J.F.; Northcote, P.; Steinmetz, M.O.; Kamimura,S.; Altmann, K-H; Paterson, I.;, Gago, F.; Van der Eycken, J.; Díaz, J.F.; Oliva, M.A.
[2023]. Chemical modulation of microtubule structure through the laulimalide/peloruside site. Structure (2023), 31, 1, 88-99.e5
Boiarska, Z.; Helena Pérez-Peña, H.; Abel, A-C.; Marzullo, P.; Álvarez-Bernad, B.; Bonato, F.; Santini, B.; Horvath, D.; Lucena-Agell, D.; Vasile, F.; Sironi, M.; Díaz, J.F.; Prota, A.E.; Pieraccini, S.; Passarella, D.
[2023]. Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics. Chemistry—A European Journal (2023), 29, e202203431
Li, S.; Mori, M; Yang, M.; Elfazazi, S.; Hortigüela, R.; Chan, P.; Feng, X.; Risinger, Q.L.; Yang, Z.; Oliva, M.A.; Diaz, J.F.; Fang, W.
[2022]. Targeting tubulin C-terminal tail by charged small molecules Org. Biomol. Chem., 2022, DOI: https://doi.org/10.1039/D2OB01910H
Oliva, M.A.; Tosat-Bitrián, C.; Barrado-Gil, L.; Bonato, F.;Galindo, I.; Urtzi Garaigorta, U.; Álvarez-Bernad, B.; París-Ogáyar, R.; Lucena-Agell, D.; Giménez-Abián, J.F.; García-Dorival, I.; Urquiza, J.; Gastaminza, P.; Díaz, J.F.*; Palomo, V.*; Alonso, C.*
[2022]. Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function (2022) Int. J. Mol. Sci. (2022) 23, 3448
Campiani,C.; Khan, T.; Ulivieri, C.; Staiano, L.; Papulino, C.; Magnano, S.; Nathwani, S.; Ramunno, A.; Lucena-Agell, D.; Relitti, N.; Federico, S.; Pozzetti, L.; Carullo, G.; Casagni, A.; Brogi, S.; Vanni, F.; Galatello, P.; Ghanim, M.; McCabe, N.; Lamponi, S.; Valoti, M.; Ibrahim,O.; O’Sullivan, J.; Turkington, R.; Kelly, V.P; VanWemmel, R.; Díaz, J.F.; Gemma, S.; Zisterer, D.; Altucci, L.; De Matteis, A.; Butini, S.; Benedetti, R.
[2022]. Design and Synthesis of Multifunctional Microtubule Targeting Agents endowed with Dual Pro-apoptotic and Anti-autophagic Efficacy. (2022) European Journal of Medicinal Chemistry. 235, 114274 https://doi.org/10.1016/j.ejmech.2022.114274
Marzullo, P.; Boiarska, Z.; Pérez-Peña, H.; Abel, A.C.; Álvarez-Bernad, B.; Lucena-Agell, D.; Vasile, F.; Sironi, M.; Altmann, K.H.; Prota, A.E.; Díaz, J.F.; Pieraccini, S.; Passarella, D.
[2022]. Maytansinol derivatives: side reactions as a chance for new tubulin binders. (2022) Chem. Eur. J. (2022) ,28, e2021035 doi.org/10.1002/chem.202103520
Alcolea, P.J.; Larraga, J.; Rodríguez-Martín, D; Alonso, A.; Loayza, F.J.; Rojas, J.M.; Ruiz-García, S; Louloudes-Lázaro, A; Carlón, A; Sánchez-Cordón, P.J.; Nogales-Altozano, P; Redondo, N; Manzano, M; Lozano, D; Palomero, J.; Montoya, M.; Vallet-Regí, M.; Martín, V.; Sevilla, N.*; Larraga, V*.
[2022]. Non-replicative antibiotic resistance-free DNA vaccine encoding S and N proteins induces full protection in mice against SARS CoV-2 Front. Immunol. (2022) 13 doi:10.3389/fimmu.2022.1023255
