Group Leader/s



Main research focus in our lab is the characterization of immune cell adhesion, migration and differentiation, and the identification of molecular mechanisms of cancer cell resistance 



Cell migration and cancer

Sevilla-Movilla S, Arellano-Sánchez N, Martínez-Moreno M, Gajate C, Sánchez-Vencells A, Vitores Valcárcel L, Agirre X, Valeri A, Martínez-López J, Prósper F,Mollinedo F and Teixidó J.  [2020]. Upregulated expression and function of the a4b1 integrin in multiple myeloma cells resistant to bortezomib. J. Pathol. 252: 29-40

Benito-Jardón L, Díaz-Martínez M, Arellano-Sánchez N, Vaquero-Morales P, Esparis-Ogando A and Teixidó J  [2019]. Resistance to MAPK inhibitors in melanoma involves activation of the IGF-1R-MEK5-Erk5 pathway. Cancer Res. 79(9): 2244-2256

Redondo-Muñoz J, García-Pardo A and Teixidó J  [2019]. Molecular players in hematological tumor cell trafficking. Frontiers in Immunol. 10:156

Teixidó J, Martínez-Moreno M, Díaz-Martínez M and Sevilla-Movilla S.  [2018]. The good and bad faces of the CXCR4 chemokine receptor. Internat. J. Biochem. Cell Biol. 95: 121-131

Díaz-Martínez M, Benito-Jardón L, Alonso L, Koetz-Ploch L, Hernando E, Teixido J.  [2018]. miR-204-5p and miR-211-5p contribute to BRAF inhibitor resistance in melanoma. Cancer Research, 78: 1017-1030.

M Martínez-Moreno, M Leiva, N Aguilera-Montilla, S Sevilla-Movilla, S I de Val, N Arellano-Sánchez, N C Gutiérrez, R Maldonado, J Martínez-López, I Buño, J A García-Marco, P Sánchez-Mateos, A Hidalgo, A García-Pardo and J Teixidó  [2016]. In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins. 2016. Leukemia, 30, 861-872

Gutiérrez-González A, Martínez-Moreno M, Samaniego R, Arellano-Sánchez N, Salinas-Muñoz L, Relloso M, Valeri A, Martínez-López J, Corbí ÁL, Hidalgo A, García-Pardo Á, Teixidó J, Sánchez-Mateos P.  [2016]. Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma. Blood. 128: 2241-2252

Sosa-Costa A, Isern de Val S, Sevilla-Movilla S, Borgman KJ, Manzo C, Teixidó J, Garcia-Parajo MF.  [2016]. Lateral Mobility and Nanoscale Spatial Arrangement of Chemokine-activated α4β1 Integrins on T Cells. J Biol Chem. 291: 21053-21062

Dios-Esponera A, Isern de Val S, Sevilla-Movilla S, García-Verdugo R, García-Bernal D, Arellano-Sánchez N, Cabañas C, Teixidó J.  [2015]. Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T lymphocyte adhesion mediated by integrin α4β1. Mol Biol Cell. 2015 Jul 22. pii: mbc.E14-07-1246. PMID: 26202465

García-Bernal D, Redondo-Muñoz J, Dios-Esponera A, Chèvre R, Bailón E, Garayoa M, Arellano-Sánchez N, Gutiérrez NC, Hidalgo A, García-Pardo A, Teixidó J  [2013]. Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function. J Pathol 229: 36-48



- Characterization of molecular mechanisms involved in thymocyte development and in melanoma cell resistance to MAP quinase inhibitors.

PID2020-116291RB-I00. 2021-2024. PI, Joaquin Teixidó 

- Characterization of molecular mechanisms involved in migration, survival and resistance to chemotherapy in multiple myeloma and melanoma. 

SAF2017-85146-R: 2018-2020. PI: Joaquin Teixidó

- Imaging, genomics and proteomics analyses of B cell hematological tumor progression

S2010/BMD-2314. Biomedicina. Comunidad de Madrid. 2012-2016. PI: Joaquin Teixido 


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