Responsable/s del laboratorio Head of lab Faustino Mollinedo Garcia Líneas de investigación Ver Proyectos actuales Ver Proyectos anteriores Research Projects Head: Faustino Mollinedo Garcia Miembros Personal Científico Faustino Mollinedo Garcia Técnicos Ramón Romero Varo Publicaciones seleccionadas Gajate, C., Mollinedo, F. [2015]. Lipid raft-mediated Fas/CD95 apoptotic signaling in leukemic cells and normal leukocytes and therapeutic implications. Journal of Leukocyte Biology. 98:739-759. Cuesta-Marbán, Á., Botet, J., Czyz, O., Cacharro, L.M., Gajate, C., Hornillos, V., Delgado, J., Zhang, H., Amat-Guerri, F., Acuña, A.U., McMaster, C.R., Revuelta, J.L., Zaremberg, V., Mollinedo, F. [2013]. Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast. Journal of Biological Chemistry. 288:8405-8418. Gajate, C., Matos-Da-Silva, M., Dakir, E.L.-H., Fonteriz, R.I., Alvarez, J., Mollinedo, F. [2012]. Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum. Oncogene. 31:2627-2639. García-Navas, R., Munder, M., Mollinedo, F. [2012]. Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes. Autophagy. 8:1557-1576. Varela-M, R.E., Villa-Pulgarin, J.A., Yepes, E., Müller, I., Modolell, M., Muñoz, D.L., Robledo, S.M., Muskus, C.E., López-Abán, J., Muro, A., Vélez, I.D., Mollinedo, F. [2012]. In vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasites. PLoS Neglected Tropical Diseases. 6:-. Mollinedo, F., De La Iglesia-Vicente, J., Gajate, C., Estella-Hermoso De Mendoza, A., Villa-Pulgarin, J.A., Campanero, M.A., Blanco-Prieto, M.J. [2010]. Lipid raft-targeted therapy in multiple myeloma. Oncogene. 29:3748-3757. Gajate, C., Mollinedo, F. [2007]. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blood. 109:711-719. Mollinedo, F., Calafat, J., Janssen, H., Martín-Martín, B., Canchado, J., Nabokina, S.M., Gajate, C. [2006]. Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. Journal of Immunology. 177:2831-2841. Gajate, C., Del Canto-Jañez, E., Acuña, A.U., Amat-Guerri, F., Geijo, E., Santos-Beneit, A.M., Veldman, R.J., Mollinedo, F. [2004]. Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis. Journal of Experimental Medicine. 200:353-365. Gajate, C., Mollinedo, F. [2001]. The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells. Blood. 98:3860-3863. Todas las publicaciones Fondos Más información Currently no information is available
Gajate, C., Mollinedo, F. [2015]. Lipid raft-mediated Fas/CD95 apoptotic signaling in leukemic cells and normal leukocytes and therapeutic implications. Journal of Leukocyte Biology. 98:739-759.
Cuesta-Marbán, Á., Botet, J., Czyz, O., Cacharro, L.M., Gajate, C., Hornillos, V., Delgado, J., Zhang, H., Amat-Guerri, F., Acuña, A.U., McMaster, C.R., Revuelta, J.L., Zaremberg, V., Mollinedo, F. [2013]. Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast. Journal of Biological Chemistry. 288:8405-8418.
Gajate, C., Matos-Da-Silva, M., Dakir, E.L.-H., Fonteriz, R.I., Alvarez, J., Mollinedo, F. [2012]. Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum. Oncogene. 31:2627-2639.
García-Navas, R., Munder, M., Mollinedo, F. [2012]. Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes. Autophagy. 8:1557-1576.
Varela-M, R.E., Villa-Pulgarin, J.A., Yepes, E., Müller, I., Modolell, M., Muñoz, D.L., Robledo, S.M., Muskus, C.E., López-Abán, J., Muro, A., Vélez, I.D., Mollinedo, F. [2012]. In vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasites. PLoS Neglected Tropical Diseases. 6:-.
Mollinedo, F., De La Iglesia-Vicente, J., Gajate, C., Estella-Hermoso De Mendoza, A., Villa-Pulgarin, J.A., Campanero, M.A., Blanco-Prieto, M.J. [2010]. Lipid raft-targeted therapy in multiple myeloma. Oncogene. 29:3748-3757.
Gajate, C., Mollinedo, F. [2007]. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blood. 109:711-719.
Mollinedo, F., Calafat, J., Janssen, H., Martín-Martín, B., Canchado, J., Nabokina, S.M., Gajate, C. [2006]. Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. Journal of Immunology. 177:2831-2841.
Gajate, C., Del Canto-Jañez, E., Acuña, A.U., Amat-Guerri, F., Geijo, E., Santos-Beneit, A.M., Veldman, R.J., Mollinedo, F. [2004]. Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis. Journal of Experimental Medicine. 200:353-365.
Gajate, C., Mollinedo, F. [2001]. The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells. Blood. 98:3860-3863.
