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Gaugaz, F.Z.; Chicca, A.; Redondo-Horcajo, M.; Barasoain, I.; Díaz, J.F.; Altmann, K.H.
[2019]. Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate. (2019). Int. J. Mol. Sci. 2019, 20, 1113
Kuzniewski, C.N.; Glauser, S.; Gaugaz, F.Z.; Schiess, R.; Rodríguez-Salarichs, J.; Vetterli, S.; Horlacher, O.P.; Gertsch, J.; Redondo-Horcajo, M.; Canales, A.; Jiménez-Barbero, J.; Díaz, J.F.; Altmann, K.H.
[2019]. Synthesis, Profiling and Bioactive Conformation of trans-Cyclopropyl Epothilones Helv. Chim. Acta 102, 5 e1900078
Balaguer, F.A.; Mühlethaler, T.; Estévez-Gallego, J.; Calvo, E.; Giménez-Abián, J.F.; Risinger, A.L.; Sorensen, E.J.; Vanderwal, C.D.; Altmann, K.-H.; Mooberry, S.L.; Steinmetz, M.O.; Oliva,M.A.; Prota, A.E.; Díaz, J.F.
[2019]. Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands (2019) Int. J. Mol. Sci. 2019, 20, 1392
Rai, A.; Liu, T.; Glauser, S.; Katrukha, E.A.; Estévez-Gallego, J.; Rodríguez-García, R.; Fang, W.S.; Díaz, J.F.; Steinmetz,M.O.; Altmann, K.H.; Kapitein, L.C.; Moore, C.A.; Akhmanova, A.
[2019]. Taxanes convert regions of perturbed microtubule growth into rescue sites (2019) Nature Materials https://doi.org/10.1038/s41563-019-0546-6
Bonandi, E.; Foschi, F.; Dapiaggi, F.; Sironi, M.; Pieraccini, S.; Christodoulou, M.S.; Balaguer, F.A.; Díaz, J.F.; Zidar, N.; Passarella, D.
[2019]. Synthesis of thicolchicine-based conjugates: investigation towards bivalent tubulin/microtubules binders ChemPlusChem 84, 98–102
Clara‐Rahola, J.; Casado‐Rodríguez, M.A,; Arrabal‐Campos, F. M.; Algarra, M.; López‐Romero, J.M.; Laurenti, M.; Fernández, I. Diaz, J.F.; , Rubio‐Retama, J.; Contreras‐Cáceres, R
[2018]. Synthesis, Characterization and Application of pH responsive Au@p4VP microgels as platform for Selective SERS Analysis. (2018) J. Colloid Interface Sci. 514, 704–714
Bueno, O.; Estévez-Gallego, J.; Martins, S.; Prota, A.E.; Gago, F.; Gómez SanJuan, A.; Camarasa, M.J.; Barasoain, I.; Steinmetz, M.O.; Díaz, J.F.; Pérez-Pérez, M.J.; Liekens, S.; Priego, E.M.
. High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design. (2018) Scientific Reports. 8, 4242
Field, J.J.; Pera, B.; Estévez-Gallego, J.; Calvo, E.; Rodríguez-Salarichs, J.; Sáez-Calvo, G.; Zuwerra, D.; Jordi, M.; Andreu, J.M.; Prota, A.E.; Ménchon, G.; Miller, J.H.; Altmann; K.H.; Díaz, J.F.
[2018]. Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites. J. Nat. Prod. (2018) 81, 3, 494-505
Bueno, O.; Tobajas, G.; Quesada, E.; Estévez-Gallego, J.; Camarasa, M.J.; Díaz, J.F.; Liekens, S.; Priego, E.M.; Pérez-Pérez, M.J.
. Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity. (2018) European Journal of Medicinal Chemistry. 148 337-348
Menchon, G.; Prota, A.E.; Lucena-Agell, D.; Bucher, P.; Jansen, R.; Irschik, H.; Mueller, R.; Paterson, I.; Diaz, J. F.; Altmann, K.H.; Steinmetz, M.O
[2018]. A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. (2018) NATURE COMMUNICATIONS. 9, 2016.
Huecas, S.; Ramírez-Aportela, E.; Vergoñós, A.; Núñez-Ramírez, R.; Llorca, O. Díaz, David; J.F.; Juan-Rodríguez, D.; Oliva, M.A.; Castellen, P.; Andreu, J.M
[2017]. Self-Organization of FtsZ Polymers in Solution Reveals Spacer Role of the Disordered C-Terminal Tail. Biophysical Journal 113, 1831–1844
Gilson, P., Josa-Prado, F., Beauvineau, C., Naud-Martin, D., Vanwonterghem, L., Mahuteau-Betzer, F., Moreno, A., Falson, P., Lafanechère, L., Frachet, V., Coll, J.-L., Fernando Díaz, J., Hurbin, A., Busser, B.
[2017]. Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties. Scientific Reports. 7: Article number 10209
Canela, M.-D., Noppen, S., Bueno, O., Prota, A.E., Bargsten, K., Sáez-Calvo, G., Jimeno, M.-L., Benkheil, M., Ribatti, D., Velázquez, S., Camarasa, M.-J., Fernando Díaz, J., Steinmetz, M.O., Priego, E.-M., Pérez-Pérez, M.-J., Liekens, S.
[2017]. Antivascular and antitumor properties of the tubulin-binding chalcone TUB091. Oncotarget. 8:14325-14342.
Bohnacker, T.; Prota, A.; Beaufils, F.; Burke, J.; Melone, A.; Inglis, A.; Rageot, D.; Sele, A.; Cmiljanovic, V; Cmiljanovic, N.; Bargsten, K.; Aher, A.; Akhmanova, A. Diaz, J.F.; Fabbro, D.; Zvelebil, M.; Williams, R.; Steinmetz, M.; and Wymann; M.
[2017]. Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nature Communications. Article number:14683
Tang, Y.; Rodríguez-Salarichs, J.; Zhao, Y.; Cai, P.; Estévez-Gallego, J.; Balaguer, F.; Redondo-Horcajo, M.; Lucena-Agell, D.; Barasoain, I.; Díaz, J.F.; Fang, W.S.
[2017]. Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by bIII-Tubulin and P-glycoprotein (P-gp) overexpressions Eur J. Med. Chem. 137 488-503
Sáez-Calvo, G.; Sharma, A.; Balaguer, F.; Barasoain, I.; Rodríguez-Salarichs, J. Olieric, N.; Muñoz-Hernández, H; Berbís, M.A.; Wendeborn, S.; Peñalva, M.A.; Matesanz, R. Canales, A.; Prota, A.E.; Jímenez-Barbero, J.; Andreu, J.M.; Lamberth, C.; Steinmetz, M.O. and Díaz, J.F.
[2017]. Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin. Cell Chemical Biology, 24 (6), 737-750