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Etxebeste-Mitxeltorena, M.; Flores-Romero, H.; Ramos-Inza, S.; Masiá, E.; Nenchova, M.; Montesinos, J.; Martinez-Gonzalez, L.; Porras, G.; Orzáez, M.; Vicent, M. J.; Gil, C.; Area-Gomez, E.; Garcia-Saez, A. J.; Martinez, A.
[2025]. Modulation of mitochondria-endoplasmic reticulum contacts (MERCs) by small molecules as a new strategy for restoring lipid metabolism in an amyotrophic lateral sclerosis model. J Med Chem 2025, 68, 1179-1194
Morales-Tenorio, M.; Lasala, F.; Garcia-Rubia, A.; Aledavood, E.; Heung, M.; Olal, C.; Escudero-Perez, B.; Alonso, C.; Martínez, A.; Muñoz-Fontela, C.; Delgado, R.; Gil, C.
[2024]. Discovery of thiophene derivatives as potent Ebola virus entry inhibitors orally bioavailable and blood-brain barrier permeable. J Med Chem 2024, 67, 16381-16402
Molina-Panadero, I.; Morales-Tenorio, M.; García-Rubia, A.; Ginex, T.; Eskandar, K.; Martinez, A.; Gil, C.; Smani, Y.
[2024]. Discovery of new antimicrobial thiophene derivatives with activity against drug-resistant Gram negative-bacteria. Front Pharmacol 2024, 15, 1412797
Carneros, E.; Berenguer, E.; Pérez-Pérez, Y.; Saurabh, P.; Welsch, R.; Palme, K.; Gil, C.; Martínez, A.; Testillano, P. S.
[2024]. Small molecule inhibitors of human LRRK2 enhance in vitro embryogenesis and microcallus formation for plant regeneration of crop and model species. J Plant Physiol 2024, 303, 154334
Atienza-Navarro, I.; del Marco, A.; Garcia-Perez, A.; Raya-Marin, A.; Gil, C.; Martinez, A.; Benavente-Fernandez, I.; Lubian-Lopez, S.; Garcia-Alloza, M.
[2024]. VP3.15 reduces acute cerebellum damage after germinal matrix-intraventricular hemorrhage of the preterm newborn. Biomed Pharmacother 2024, 180, 117586
Pérez de la Lastra Aranda, C.; Tosat-Bitrián, C.; Porras, G.; Dafinca, R.; Muñoz-Torrero, D.; Talbot, K.; Martín-Requero, Á.; Martínez, A.; Palomo, V.
[2024]. Proteome aggregation in cells derived from amyotrophic lateral sclerosis patients for personalized drug evaluation. ACS Chem Neurosci 2024, 15, 3945-3953
Grieco, I.; Bassani, D.; Trevisan, L.; Salmaso, V.; Cescon, E.; Prencipe, F.; Da Ros, T.; Martinez-Gonzalez, L.; Martinez, A.; Spalluto, G.; Moro, S.; Federico, S.
[2024]. 7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions. Bioorg Chem 2024, 151, 107659
Nozal, V.; Fernández-Gómez, P.; García-Rubia, A.; Martínez-González, L.; Cuevas, E. P.; Carro, E.; Palomo, V.; Martínez, A.
[2024]. Designing multitarget ligands for neurodegenerative diseases with improved permeability trough PLGA nanoencapsulation. Biomed Pharmacother 2024, 175, 116626
Santi, M. D.; Carvalho, D.; Dapueto, R.; Bentura, M.; Zeni, M.; Martínez-González, L.; Martínez, A.; Peralta, M. A.; Rey, A.; Giglio, J.; Ortega, M. G.; Savio, E.; Abin-Carriquiry, J. A.; Arredondo, F.
[2024]. Prenylated flavanone isolated from Dalea species as a potential multitarget-neuroprotector in an in vitro Alzheimer's disease mice model. Neurotox Res 2024, 42, 23
García-Cuesta, E. M.; Martínez, P.; Selvaraju, K.; Gómez-Pozo, A.M.; D’Agostino, G.; Gardeta, S.; Quijada-Freire, A.; Blanco-Gabella, P.; Roca, C.; Jiménez-Saiz, R.; García-Rubia, A.; Soler-Palacios, B.; Lucas, P.; Ayala-Bueno, R.; Santander-Acerete, N.; Carrasco, Y.R.; Martínez, A.; Campillo, N. E.; Jenssen, L.; Rodríguez-Frade, J. M.; Santiago, C.; Mellado, M.
[2024]. Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain. eLife, 2024, 13, RP93968
Cuevas, E. P.; Martinez-Gonzalez, L.; Gordillo, C.; Tosat-Bitrián, C.; Pérez de la Lastra, C.; Sáenz, A.; Gil, C.; Palomo, V.; Martin-Requero, A.; Martinez, A.
[2024]. Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosis. Neurobiol Dis 2024, 192, 106430
Etxebeste-Mitxeltorena, M.; Niza, E.; Martinez-Fajardo, C.; Gil, C.; Gómez-Gómez, L.; Martinez, A.; Ahrazem, O.
[2024]. Neuroprotective properties of exosomes and chitosan nanoparticles of Tomafran, a bioengineered tomato enriched in crocins. Nat Prod Bioprospect 2024, 14, 9
Benítez-Fernández, R.; Josa-Prado, F.; Sánchez, E.; Lao, Y.; García-Rubia, A.; Cumella, J.; Martínez, A.; Palomo, V.; de Castro, F.
[2024]. Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis. CNS Neurosci Ther 2024, 30, e14552
Atienza-Navarro, I.; del Marco, A.; Alves-Martinez, P.; Garcia-Perez, A.; Raya-Marin, A.; Benavente-Fernandez, I.; Gil, C.; Martinez, A.; Lubian-Lopez, S.; Garcia-Alloza, M.
[2024]. Glycogen synthase kinase-3β inhibitor VP3.15 ameliorates neurogenesis, neuronal loss and cognitive impairment in a model of germinal matrix- intraventricular hemorrhage of the preterm newborn. Transl Stroke Res 2024, doi 10.1007/s12975-023-01229-2
Garcia-Rubia, A.; Lasala, F.; Ginex, T.; Morales-Tenorio, M.; Olal, C.; Heung, M.; Oquist, P.; Galindo, I.; Cuesta-Geijo, M.; Casasnovas, J. M.; Campillo, N. E.; Canales, Á.; Alonso, C.; Martínez, A.; Muñoz-Fontela, C.; Delgado, R.; Gil, C.
[2023]. N'-Phenylacetohydrazide derivatives as potent Ebola virus entry inhibitors with an improved pharmacokinetic profile. J Med Chem 2023, 66, 8, 5465-5483
Martinez-Gonzalez, L.; Cuevas, E. P.; Tosat, C.; Nozal, V.; Gil, C.; Palomo, V.; Martin-Requero, A.; Martinez, A.
[2023]. TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer's disease patients. Front Mol Neurosci 2023, 16, 1243277
