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Lasala, F.; García-Rubia, A.; Requena, C.; Galindo, I.; Cuesta-Geijo, M. A.; García-Dorival, I.; Bueno, P.; Labiod, N.; Luczkowiak, J.; Martinez, A.; Campillo, N. E.; Alonso, C.; Delgado, R.; Gil, C.
[2021]. Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses. Antiviral Res. 2021, 186, 105011.
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[2021]. Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and Amyotrophic Lateral Sclerosis (ALS). J Neurochem 2021, 156, 379-390.
Galindo, I.; Garaigorta, U.; Lasala, F.; Cuesta-Geijo, M. A.; Bueno, P.; Gil, C.; Delgado, R.; Gastaminza, P.; Alonso, C.
[2021]. Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses. Antiviral Res. 2021, 186, 104990.
Morales-Tenorio, M.; Ginex, T.; Cuesta-Geijo, M. A.; Campillo, N. E.; Muñoz-Fontela, C.; Alonso, C.; Delgado, R.; Gil, C.
[2021]. Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction. Eur J Med Chem 2021, 223, 113654.
Ginex, T.; Garaigorta, U.; Ramírez, D.; Castro, V.; Nozal, V.; Maestro, I.; García-Cárceles, J.; Campillo, N. E.; Martinez, A.; Gastaminza, P.; Gil, C.
[2021]. Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods. Pharmaceuticals 2021, 14, 332.
Nozal, V.; García-Rubia, A.; Cuevas, E. P.; Pérez, C.; Tosat-Bitrián, C.; Bartolomé, F.; Carro, E.; Ramírez, D.; Palomo, V.; Martínez, A.
[2021]. From kinase inhibitors to multitarget ligands as powerful drug leads for Alzheimer's disease using protein-templated synthesis. Angew Chem Int Ed Engl 2021, 60 (35), 19344-19354.
García-Dorival, I.; Cuesta-Geijo, M. A.; Barrado-Gil, L.; Galindo, I.; Garaigorta, U.; Urquiza, J.; Del Puerto, A.; Campillo, N.; Martínez, A.; Gastaminza, P.; Gil, C.; Alonso, C.
[2021]. Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target. Antiviral Res 2021, 194, 105167.
Rojas-Prats, E.; Tosat-Bitrián, C.; Martínez-González, L.; Nozal, V.; Pérez, D. I.; Martínez, A.
[2021]. Increasing brain permeability of PHA-767491, a cell division cycle 7 kinase inhibitor, with biodegradable polymeric nanoparticles. Pharmaceutics 2021, 13 (2), 180.
Lastres-Becker, I.; Porras, G.; Arribas-Blázquez, M.; Maestro, I.; Borrego-Hernández, D.; Boya, P.; Cerdán, S.; García-Redondo, A.; Martínez, A.; Martin-Requero, Á.
[2021]. Molecular alterations in sporadic and SOD1-ALS immortalized lymphocytes: Towards a personalized therapy. Int J Mol Sci 2021, 22 (6), 3007.
Rico, A.; Guembelzu, G.; Palomo, V.; Martínez, A.; Aiastui, A.; Casas-Fraile, L.; Valls, A.; López de Munain, A.; Sáenz, A.
[2021]. Allosteric modulation of GSK-3β as a new therapeutic approach in limb girdle muscular dystrophy R1 calpain 3-related. Int J Mol Sci 2021, 22 (14), 7367
Grieco, I.; Bissaro, M.; Tiz, D. B.; Perez, D. I.; Perez, C.; Martinez, A.; Redenti, S.; Mariotto, E.; Bortolozzi, R.; Viola, G.; Cozza, G.; Spalluto, G.; Moro, S.; Federico, S.
[2021]. Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems. Eur J Med Chem 2021, 216, 113331.
Davies, M. P.; Benitez, R.; Perez, C.; Jakupovic, S.; Welsby, P.; Rzepecka, K.; Alder, J.; Davidson, C.; Martinez, A.; Hayes, J. M.
[2021]. Structure-based design of potent selective nanomolar type-II inhibitors of glycogen synthase kinase-3β. J Med Chem 2021, 64 (3), 1497-1509.