Calvo E, Camafeita E, Díaz JF and López JA
[2008]. Mass Spectrometry for Studying the Interaction between Small Molecules and Proteins, Current Proteomics 5:20-34
Bai R, Vanderwaal CD, Díaz JF, Hamel E
[2008]. The interaction of a cyclostreptin analogue with the microtubule: The covalent reaction rapidly follows binding. J Natl Prod 71, 370-374
Matesanz R, Barasoain I, Yang CG, Wang L, Li X, de Inés C, Coderch C, Gago F, Jiménez-Barbero J, Andreu JM, Fang WS and Díaz JF
[2008]. Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel. Chem Biol 15, 573-585
Buey RM, Chacón P, Andreu JM and Díaz JF
[2008]. Protein shape and assembly studied with X ray solution scattering: Fundaments and practice. Lecture Notes in Physics. Applications of Synchrotron Light to Non-Crystalline Diffraction in Materials and Life Sciences, Springer Berlin / Heidelberg pp:226-244
Díaz JF, Andreu JM and Jiménez-Barbero J
[2008]. The interaction of microtubules with stabilizers characterized at biochemical and structural levels. Topics in Current Chemistry DOI:10.1007/128_2008_12
Canales A, Matesanz R, Gardner NM, Andreu JM, Paterson I, Díaz JF, Jiménez-Barbero J
[2008]. The bound conformation of microtubule-stabilizing agents (II): NMR insights on the bioactive 3D structure of discodermolide and dictyostatin. Chemistry Eur J. 1414, 7557-7569
García-Fortanet J, Murga J, Carda M , Marco JA, Matesanz R, Díaz JF and Barasoain I
[2007]. The Total Synthesis and Biological Properties of the Cytotoxic Macrolide FD-891 and Its Non-Natural (Z)-C12 Isomer. Chem Eur J 13:5060–5074
La Regina G, Edler MC, Brancale A, Kandil A, Coluccia A, Piscitelli F, Hamel E, De Martino G, Matesanz R, Díaz JF, Scovassi AI, Prosperi E, Lavecchia A, Novellino E, Artico M, Silvestri R
[2007]. Arylthioindole Inhibitors of Tubulin Polymerization. 3. Biological Evaluation, Structure-Activity Relationships and Molecular Modeling Studies. J Med Chem 50:2865-2874
Wang L, Alcaraz AA, Matesanz R, Yang CG, Barasoain I, Díaz JF ,Li YZ,Snyder JP, Fang WS
[2007]. Synthesis, biological evaluations, and tubulin binding poses of C-2a sulfur linked taxol analogues. Bioorg Med Chem Lett 17:3191–3194
Buey RM, Monterroso B, Menéndez, M, Diakun G, Chacón P, Hermoso JA, Díaz JF
[2007]. Insights into Molecular Plasticity of Choline Binding. J Mol Biol 365:411-424
Yang, C.G., Barasoain, I., Li, X., Matesanz, R., Liu, R., Sharom, F.J., Yin, D.L., Díaz, J.F. and Fang, W.S.
[2007]. Overcoming Tumor Drug Resistance Mediated by P-glycoprotein Overexpression and beta-Tubulin Mutations with High Affinity Taxanes: A Structure Activity Relationship Study of C-2 Modified 7-Acyl-10-Deacetyl Cephalomannines. Chem Med Chem 2:691-701
Díaz, J.F. and Buey, R.M.
[2007]. Characterizing Ligand-Microtubule binding by competition methods. Microtubule Protocols Methods in Molecular Medicine 137 (J. Zhou, Ed.) Humana Press, pp 245-260
Buey R, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal, CD, Day BW, Sorensen EJ, Lopez JA, Andreu JM, Hamel E, Díaz F
[2007]. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nature Chemical Biology 3, 117-125 and cover
Buey, R.M., Díaz, J.F. and Andreu, J.M.
[2006]. The nucleotide switch of tubulin and microtubule assembly: A polymerization-driven structural change. Biochemistry 45, 5933-5938
Jiménez-Barbero, J., Canales, A., Northcote, P.T., Buey, R.M., Andreu, J.M. and Díaz, J.F.
[2006]. NMR determination of the bioactive conformation of Peloruside A bound to microtubules. JACS 128, 8757-8765.
Marcus, A.I., O’ Brate, A.M., Buey, R.M., Zhou, J., Thomas, S., Khuri, F.R., Andreu, J.M., Díaz, J.F. and Giannakakou
[2006]. Farnesyl transferase inhibitors reverse taxane-resistence. Cancer Research 66, 8838-8846.
Buey RM, Barasoain I, Jackson M, Meyer A, Giannakakou P, Paterson I, Mooberry S, Andreu JM, Díaz JF
[2005]. Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicity. Chem Biol 12:1269-1279
Paterson, I, Menche, D, Håkansson, A.E., Longstaff, A., Wong, D., Barasoain, I., Buey, R.M. and Díaz. J.F.
[2005]. Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain. Bioorg. Med. Chem. Lett 15 (9) 2243-2247.
Edler, M.C., Buey, R.M., Gussio, R., Marcus, A.I., VanderWal, C.D., Sorensen, E.J., Díaz, J.F., Giannakakou, P., and Hamel., E.
[2005]. Cyclostreptin (FR182877), an Antitumour Tubulin-Polymerizing Agent Deficient in Enhancing Tubulin Assembly Despite Its High Affinity for the Taxoid Site Biochemistry 44, 11525-11538
Diaz JF, Barasoain I, Souto AA, Amat-Guerri F, Andreu JM
[2005]. Macromolecular accessibility of fluorescent taxoids bound at a paclitaxel binding site in the microtubule surface. J Biol Chem 280: 3928-3937
