Responsable/s del laboratorio Head of lab Annamaria Ruggiano Líneas de investigación Ver Proyectos actuales Ver Proyectos anteriores Miembros Investigador Ramón y Cajal Annamaria Ruggiano Visitantes Rodrigo Casas Torreblanca Publicaciones seleccionadas Torrecilla, I.#, Ruggiano, A.#, Kiianitsa, K., Aljarbou, F., Lascaux, P., Hoslett, G., Song, W., Maizels, N., Ramadan, K. [2024]. Isolation and detection of DNA–protein crosslinks in mammalian cells. Nucleic Acids Research. 52:525-547. Lascaux, P., Hoslett, G., Tribble, S., Trugenberger, C., Antičević, I., Otten, C., Torrecilla, I., Koukouravas, S., Zhao, Y., Yang, H., Aljarbou, F., Ruggiano, A., Song, W., Peron, C., Deangeli, G., Domingo, E., Bancroft, J., Carrique, L., Johnson, E., Vendrell, I., Fischer, R., Ng, A.W.T., Ngeow, J., D'Angiolella, V., Raimundo, N., Maughan, T., Popović, M., Milošević, I., Ramadan, K. [2024]. TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival. Cell. 187:5698-5718.e26. Ruggiano, A.#, Vaz, B.#, Kilgas, S., Popović, M., Rodriguez-Berriguete, G., Singh, A.N., Higgins, G.S., Kiltie, A.E., Ramadan, K. [2021]. The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Cell Reports. 37:-. Ruggiano, A., Ramadan, K. [2021]. DNA–protein crosslink proteases in genome stability. Communications Biology. 4:-. Ruggiano, A., Ramadan, K. [2021]. The Trinity of SPRTN Protease Regulation. Trends in Biochemical Sciences. 46:2-4. Fielden, J., Wiseman, K., Torrecilla, I., Li, S., Hume, S., Chiang, S.-C., Ruggiano, A., Narayan Singh, A., Freire, R., Hassanieh, S., Domingo, E., Vendrell, I., Fischer, R., Kessler, B.M., Maughan, T.S., El-Khamisy, S.F., Ramadan, K. [2020]. TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. Nature Communications. 11:-. Fielden, J.#, Ruggiano, A.#, Popović, M., Ramadan, K. [2018]. DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans. DNA Repair. 71:198-204. Todas las publicaciones Fondos Más información Currently no information is available
Torrecilla, I.#, Ruggiano, A.#, Kiianitsa, K., Aljarbou, F., Lascaux, P., Hoslett, G., Song, W., Maizels, N., Ramadan, K. [2024]. Isolation and detection of DNA–protein crosslinks in mammalian cells. Nucleic Acids Research. 52:525-547.
Lascaux, P., Hoslett, G., Tribble, S., Trugenberger, C., Antičević, I., Otten, C., Torrecilla, I., Koukouravas, S., Zhao, Y., Yang, H., Aljarbou, F., Ruggiano, A., Song, W., Peron, C., Deangeli, G., Domingo, E., Bancroft, J., Carrique, L., Johnson, E., Vendrell, I., Fischer, R., Ng, A.W.T., Ngeow, J., D'Angiolella, V., Raimundo, N., Maughan, T., Popović, M., Milošević, I., Ramadan, K. [2024]. TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival. Cell. 187:5698-5718.e26.
Ruggiano, A.#, Vaz, B.#, Kilgas, S., Popović, M., Rodriguez-Berriguete, G., Singh, A.N., Higgins, G.S., Kiltie, A.E., Ramadan, K. [2021]. The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Cell Reports. 37:-.
Ruggiano, A., Ramadan, K. [2021]. DNA–protein crosslink proteases in genome stability. Communications Biology. 4:-.
Ruggiano, A., Ramadan, K. [2021]. The Trinity of SPRTN Protease Regulation. Trends in Biochemical Sciences. 46:2-4.
Fielden, J., Wiseman, K., Torrecilla, I., Li, S., Hume, S., Chiang, S.-C., Ruggiano, A., Narayan Singh, A., Freire, R., Hassanieh, S., Domingo, E., Vendrell, I., Fischer, R., Kessler, B.M., Maughan, T.S., El-Khamisy, S.F., Ramadan, K. [2020]. TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. Nature Communications. 11:-.
Fielden, J.#, Ruggiano, A.#, Popović, M., Ramadan, K. [2018]. DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans. DNA Repair. 71:198-204.
