A soluble bacterial lipocalin increases resistance to diverse antibiotics in vitro and in vivo upon exposure to sublethal antibiotic concentrations.
23 Mar 2017
16 Mar 2017
One of the mechanisms that determine how cells enter latency when nutrients lack has been revealed in a paper published at eLife by scientists at the Center for Biological Research (CIB-CSIC), in collaboration with the Institute of Functional Biology (CSIC-USAL) in Salamanca and the IRB Barcelona.
09 Mar 2017
BKM120 (Buparlisib) is one of the most advanced phosphoinositide 3-kinase (PI3K) inhibitors used for the treatment of cancer. Now, BKM120 has been also shown to act as a microtubule disrupting agent.
A new family of relaxases has been identified which are involved in transferring antibiotic resistance
23 Feb 2017
The phenomenon of antibiotic resistance and its spread is one of the most important threats to health
14 Feb 2017
Last February 13th Professor Roberto Parrilla passed away at the age of 75, after a short stay at the hospital.
09 Feb 2017
Cancer metastasis is the major cause of cancer-associated death. Despite intensive research in this field, regulatory mechanisms that control metastatic spread and organ colonization are far from being understood.
New molecule with the ability to modify the number of synaptic contacts between neurons has been identified
27 Jan 2017
The work has been published recently in the PNAS journal.
Identification of a new component of meiotic synaptonemal complex essential for fertility in mammals
25 Nov 2016
The new protein is essential for the production of spermatozoids and eggs and the severe alteration of its genetic recombination rate can cause human infertility and Down syndrome
16 Nov 2016
Multiple myeloma (MM) is a B-cell neoplasia characterized by the accumulation in the bone marrow of malignant plasma cells that produce monoclonal proteins and cause bone lesions, renal disease and immunodeficiency.
04 Nov 2016
The new signal transduction system, the TolR protein is involved in the resistance to toxic aromatic compounds as toluene in a bacterium, Azoarcus sp. CIB, able to degrade these compounds anaerobically
The assembly switch of cell division protein FtsZ demonstrated: a subunit structural change that can be modulated with small antibacterial molecules
27 Oct 2016
FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division. This protein assembly machine works cooperatively polymerizing into single-stranded filaments, by means of self-switching between inactive and actively associating monomer conformations.
27 Oct 2016
The antibiotic resistance is often transferred from one bacterium to another through the genetic mobile elements.