Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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Hornillos, V.; Saugar, J. M.; de la Torre, B. G.; Andreu, D.; Rivas, L.; Acuña, A. U.; Amat-Guerri, F. [2006]. Synthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity. Bioorg Med Chem Lett 2006, 16, 5190-3.

Arias, C.; Guizy, M.; Luque-Ortega, J. R.; Guerrero, E.; de la Torre, B. G.; Andreu, D.; Rivas, L.; Valenzuela, C. [2006]. The induction of NOS2 expression by the hybrid cecropin A-melittin antibiotic peptide CA(1-8)M(1-18) in the monocytic line RAW 264.7 is triggered by a temporary and reversible plasma membrane permeation. Biochim Biophys Acta 2006, 1763, 110-9.

Mangoni, M. L.; Papo, N.; Saugar, J. M.; Barra, D.; Shai, Y.; Simmaco, M.; Rivas, L [2006]. Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H. Biochemistry 2006, 45, 4266-76

Rodríguez-Hernández, M. J.; Saugar, J.; Docobo-Pérez, F.; de la Torre, B. G.; Pachón-Ibañez, M. E.; García-Curiel, A.; Fernández-Cuenca, F.; Andreu, D.; Rivas, L.; Pachon, J. [2006]. Studies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii. J Antimicrob Chemother 2006, 58, 95-100

Saugar, J. M.; Rodriguez-Hernandez, M. J.; de la Torre, B. G.; Pachon-Ibanez, M. E.; Fernandez-Reyes, M.; Andreu, D.; Pachon, J.; Rivas, L [2006]. Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action. Antimicrob Agents Chemother 2006, 50, 1251-6.

Caparrós E, Serrano D, Puig-Kroger A, Riol L, Lasala F, Martínez I, Vidal-Vanaclocha F, Delgado R, Rodríguez-Fernandez JL, Rivas L, Corbí AL,Colmenares M [2005]. Role of the C-type lectins DC-SIGN and L-SIGN in Leishmania interaction with host phagocytes. Immunobiology, 210:185-93.

Mangoni, M. L.; Saugar, J. M.; Dellisanti, M.; Barra, D.; Simmaco, M.; Rivas, L [2005]. Temporins, small antimicrobial peptides with leishmanicidal activity. J Biol Chem 2005, 280, 984-90

Tomás, P., Jiménez-Jiménez, J., Zaragoza, P., Vuligonda, V., Chandraratna, R.A.S., Rial, E. [2004]. Activation by retinoids of the uncoupling protein UCP1. Biochimica et Biophysica Acta - Bioenergetics. 1658:157-164.

Alberola J, Rodríguez A, Francino O, Roura X, Rivas L, Andreu D [2004]. Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis. Antimicrob Agents Chemother. 48:641-3.

Colmenares M, Corbí AL, Turco SJ, Rivas L. [2004]. The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania.J. Immunol. 172:1186-90

Luque-Ortega JR, Martínez S, Saugar JM, Izquierdo LR, Abad T, Luis JG,Piñero J, Valladares B, Rivas L. [2004]. Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria.....Antimicrob Agents Chemother.48:1534-40

Puig-Kroger A, Serrano-Gómez D, Caparrós E, Domínguez-Soto A, Relloso M,Colmenares M, Martínez-Muñoz L, Longo N, Sánchez-Sánchez N, Rincón M, Rivas L, Sánchez-Mateos P, Fernández-Ruiz E, Corbí AL [2004]. Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.J Biol Chem. 279:25680-8.

Rivas L, Moreno J, Cañavate C, Alvar J. [2004]. Virulence and disease in leishmaniasis: what is relevant for the patient?Trends Parasitol. ;20(:297-301.

Guerrero, E.; Saugar, J.M.; Matsuzaki, K., Rivas, L. [2004]. Role of positional hydrophobicity in the leishmanicidal activity of magainin 2. Antimicrob. Agents Chemother. 48:2980-6.

Carretero M, Del Río M, García M, Escámez MJ, Mirones I, Rivas L, Balague C, [2004]. A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides.FASEB J. ;18:1931-3

Plasencia I, Rivas L, Keough KM, Marsh D, Pérez-Gil J [2003]. The N-terminal segment of pulmonary surfactant lipopeptide SP-C has intrinsic propensity to interact with and perturb phospholipid bilayers.Biochem J. 377:183-93.

Rivas, L ., Andreu, D. [2003]. Cecropin-melittin hybrid peptides as versatile templates in the development of membrane active antibiotics agents. In: Pore-forming peptides and protein toxins. G. Menestrina and M. Dalla Serra eds. (Reading Berkshire, Harwood Academic Publishers), pp 21

Luque-Ortega JR, Saugar JM, Chiva C, Andreu D, Rivas L. [2003]. Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP.

Bayo N, Jiménez JC, Rivas L, Nicolas E, Albericio F [2003]. Solid-phase synthesis of the cyclic lipononadepsipeptide [N-Mst(Ser1), d-Ser4, L-Thr6, L-Asp8, L-Thr9]syringotoxin.

Saugar JM, Alarcon T, López-Hernández S, López-Brea M, Andreu D, Rivas L. [2002]. Activities of polymyxin B and cecropin A-,melittin peptide CA(1-8)M(1-18) against a multiresistant strain of Acinetobacter baumannii. Antimicrob Agents Chemother. 46:875-8.