Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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Carvalho, L., Luque-Ortega, J.R., Manzano, J.I., Castanys, S., Rivas, L., Gamarro, F. [2010]. Tafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosis.[2010] Antimicrob. Agents Chemother. 54:5344-51.

Luque-Ortega, J.R., Cruz, L.J., Albericio, F., Rivas, L. [2010]. The antitumoral depsipeptide IB-01212 kills Leishmania through an apoptosis-like process involving intracellular targets.[2010] Mol. Pharm. 7:1608-1617.

Fernández-Reyes, M., Díaz, D., de la Torre, B.G., Cabrales-Rico, A., Vallès-Miret, M. Jiménez-Barbero J, Andreu, D., Rivas, L. [2010]. Lysine N(epsilon)-trimethylation, a tool for improving the selectivity of antimicrobial peptides.[2010] J. Med. Chem., 53:5587-5596

Solanas, C; de la Torre, B.G., Fernández-Reyes M., Santiveri CM, Jiménez MA, Rivas L, Jiménez AI, Andreu D, Cativiela C. [2010]. Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S.[2010] J. Med. Chem. 53:4119-4129

Luque-Ortega, J.R., Reuther, P., Rivas, L., Dardonville, C. [2010]. New Benzophenone-Derived Bisphosphonium Salts as Leishmanicidal Leads Targeting Mitochondria through Inhibition of Respiratory Complex II.[2010] J. Med. Chem. 53, 1788-1798

Rial, E., Zardoya, R. [2009]. Oxidative stress, thermogenesis and evolution of uncoupling proteins. Journal of Biology. 8:-.

Berrocal-Lobo M, Molina A, Rodríguez-Palenzuela P, García-Olmedo F, Rivas L. [2009]. Leishmania donovani: thionins, plant antimicrobial peptides with leishmanicidal activity. Exp Parasitol. (2009) 122:247-249.

Cruz, L.J., Luque-Ortega, J.R., Rivas, L., Albericio, F. [2009]. Kahalalide F, an antitumor depsipeptide in clinical trials, and its analogues as effective antileishmanial agents. Mol. Pharm. (2009) 6:813-824.

Anedda, A., Rial, E., González-Barroso, M.M. [2008]. Metformin induces oxidative stress in white adipocytes and raises uncoupling protein 2 levels. Journal of Endocrinology. 199:33-40.

Fernández-Reyes, M., Rodríguez-Falcón, M., Chiva, C., Pachón, J., Andreu, D., Rivas L. [2009]. e cost of resistance to colistin in Acinetobacter baumannii: a proteomic perspective.Proteomics. (2009) 9:1632-45.

Garcia-Verdugo, I., Garcia de Paco, E., Espinassous, Q., Gonzalez-Horta, A., Synguelakis, M., Kanellopoulos, J., Rivas, L., Chaby, R., Perez-Gil, J. [2009]. Synthetic peptides representing the N-terminal segment of surfactant protein C modulate LPS-stimulated TNF-alpha production by macrophages. Innate Immun. (2009)15:53-62.

Rivas, L., Luque-Ortega, J.R., Andreu, D. [2009]. Amphibian antimicrobial peptides and Protozoa: lessons from parasites.Biochim. Biophys. Acta. (2009),1788:1570-1581.

Hornillos, V., Carrillo, E., Rivas, L., Amat-Guerri, F., Acuña, AU. [2008]. Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine. Bioorg. Med. Chem. Lett. (2008), 18:6336-63399.

Solanas, C., de la Torre, B.G., Fernández-Reyes, M., Santiveri, C.M., Jiménez, M.A., Rivas, L., Jiménez, A.I., Andreu, D., Cativiela, C.. [2009]. Therapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn. J. Med. Chem. (2009), 52:664-674.

Luque-Ortega JR, Van´t Hof W, Veerman EC, Saugar JM, Rivas L [2008]. Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania. FASEB J, 22:1817-1828

Saugar, J.M., Delgado, J., Hornillos, V., Luque-Ortega, J.R., Amat-Guerri, F., Acuña, A.U.; Rivas, L [2007]. Synthesis and biological evaluation of fluorescent leishmanicidal analogues of hexadecylphosphocholine (miltefosine) as probes of antiparasite mechanisms.J Med Chem. 50:5994-6003

Serrano-Gómez, D;, Martínez-Nuñez, R.T.; Sierra-Filardi, E.; Izquierdo, N; Colmenares, M.; Pla, J.; Rivas, L., Martinez-Picado, J.; Jimenez-Barbero, J.; Alonso-Lebrero, J.L.; González, S.; Corbí, A.L.. [2007]. AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN. Antimicrob. Agents Chemother. 51:2313-23

Llull, D., Rivas, L., García E. [2007]. In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci. Antimicrob. Agents Chemother. 51:1844-8

Luque-Ortega JR, Rivas L [2007]. Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes. Antimicrob Agents Chemother 51:1327-32

Jiménez-Jiménez, J., Zardoya, R., Ledesma, A., García de Lacoba, M., Zaragoza, P., Mar González-Barroso, M., Rial, E. [2006]. Evolutionarily Distinct Residues in the Uncoupling Protein UCP1 Are Essential for Its Characteristic Basal Proton Conductance. Journal of Molecular Biology. 359:1010-1022.